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Quality and Characteristics of 4241 Case Reports of Lactic Acidosis in Metformin Users Reported to a Large Pharmacovigilance Database

OBJECTIVE: Metformin-associated lactic acidosis (MaLA) occurs rarely and is thus difficult to study. We analysed 4241 individual case safety reports of lactic acidosis (LA) that implicated metformin as a suspected drug reported to the pharmacovigilance database of Merck KGaA, Darmstadt, Germany. The...

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Detalles Bibliográficos
Autores principales: Brand, Kerstin M G, Schlachter, Judith, Foch, Caroline, Boutmy, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642855/
https://www.ncbi.nlm.nih.gov/pubmed/36389204
http://dx.doi.org/10.2147/TCRM.S372430