Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair

The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive.

Detalles Bibliográficos
Autor principal: Lang, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642860/
https://www.ncbi.nlm.nih.gov/pubmed/36346786
http://dx.doi.org/10.1371/journal.pbio.3001874
Descripción
Sumario:The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive.

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