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Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair

The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive.

Detalles Bibliográficos
Autor principal: Lang, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642860/
https://www.ncbi.nlm.nih.gov/pubmed/36346786
http://dx.doi.org/10.1371/journal.pbio.3001874
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author Lang, Andrew S.
author_facet Lang, Andrew S.
author_sort Lang, Andrew S.
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description The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive.
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spelling pubmed-96428602022-11-15 Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair Lang, Andrew S. PLoS Biol Primer The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive. Public Library of Science 2022-11-08 /pmc/articles/PMC9642860/ /pubmed/36346786 http://dx.doi.org/10.1371/journal.pbio.3001874 Text en © 2022 Andrew S. Lang https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Lang, Andrew S.
Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair
title Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair
title_full Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair
title_fullStr Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair
title_full_unstemmed Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair
title_short Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair
title_sort virus-derived gene transfer agents benefit host cells by providing templates for dna repair
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642860/
https://www.ncbi.nlm.nih.gov/pubmed/36346786
http://dx.doi.org/10.1371/journal.pbio.3001874
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