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Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair
The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642860/ https://www.ncbi.nlm.nih.gov/pubmed/36346786 http://dx.doi.org/10.1371/journal.pbio.3001874 |
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author | Lang, Andrew S. |
author_facet | Lang, Andrew S. |
author_sort | Lang, Andrew S. |
collection | PubMed |
description | The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive. |
format | Online Article Text |
id | pubmed-9642860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-96428602022-11-15 Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair Lang, Andrew S. PLoS Biol Primer The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with DNA damage to perform DNA repair and survive. Public Library of Science 2022-11-08 /pmc/articles/PMC9642860/ /pubmed/36346786 http://dx.doi.org/10.1371/journal.pbio.3001874 Text en © 2022 Andrew S. Lang https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Primer Lang, Andrew S. Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair |
title | Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair |
title_full | Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair |
title_fullStr | Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair |
title_full_unstemmed | Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair |
title_short | Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair |
title_sort | virus-derived gene transfer agents benefit host cells by providing templates for dna repair |
topic | Primer |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642860/ https://www.ncbi.nlm.nih.gov/pubmed/36346786 http://dx.doi.org/10.1371/journal.pbio.3001874 |
work_keys_str_mv | AT langandrews virusderivedgenetransferagentsbenefithostcellsbyprovidingtemplatesfordnarepair |