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Disseminated Mycobacterium Tuberculosis and IgA Nephropathy

Mycobacterium tuberculosis (MTB) is an under-recognised cause of genitourinary disease. IgA nephropathy (IgAN), a leading cause of glomerulonephritis worldwide, has been described as a rare consequence of disseminated MTB infection. In this case report, we present the first case of MTB associated Ig...

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Detalles Bibliográficos
Autores principales: Audley, Gordon, Davidson, Bianca, Jones, Erika, Price, Brendon, Rayner, Brian, Wearne, Nicola, Barday, Zibya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643053/
https://www.ncbi.nlm.nih.gov/pubmed/36385747
http://dx.doi.org/10.1155/2022/3785713
Descripción
Sumario:Mycobacterium tuberculosis (MTB) is an under-recognised cause of genitourinary disease. IgA nephropathy (IgAN), a leading cause of glomerulonephritis worldwide, has been described as a rare consequence of disseminated MTB infection. In this case report, we present the first case of MTB associated IgAN in Africa. Finding IgAN on kidney biopsy in an MTB endemic area should prompt a thorough investigation for MTB to increase the chance of remission of IgAN and prevent inappropriate use of immunosuppression.