Cargando…

The distillation method: A novel approach for analyzing randomized trials when exposure to the intervention is diluted

OBJECTIVE: To introduce a novel analytical approach for randomized controlled trials that are underpowered because of low participant enrollment or engagement. DATA SOURCES: Reanalysis of data for 805 patients randomized as part of a pilot complex care intervention in 2015–2016 in a large delivery s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adams, John L., Davis, Anna C., Schneider, Eric C., Hull, Michaela M., McGlynn, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2022
Materias:	Methods Corner
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643092/ https://www.ncbi.nlm.nih.gov/pubmed/35752926 http://dx.doi.org/10.1111/1475-6773.14014

Ejemplares similares

When face-to-face interviews are not possible: tips and tricks for video, telephone, online chat, and email interviews in qualitative research
por: Saarijärvi, Markus, et al.
Publicado: (2021)

Process evaluation of complex cardiovascular interventions: How to interpret the results of my trial?
por: Saarijärvi, Markus, et al.
Publicado: (2020)

Describing and assessing a new method of approximating categorical individual‐level income using community‐level income from the census (weighting by income probabilities)
por: Kim, Uriel, et al.
Publicado: (2022)

Impact of nonphysician providers on spatial accessibility to primary care in Iowa
por: Young, Sean G., et al.
Publicado: (2020)

Validation analysis of a composite real‐world mortality endpoint for patients with cancer in the United States
por: Zhang, Qianyi, et al.
Publicado: (2021)

Classifiers and their Metrics Quantified
por: Brown, J. B.
Publicado: (2018)

A comparison of methods for health policy evaluation with controlled pre‐post designs
por: O'Neill, Stephen, et al.
Publicado: (2020)

A guide to improve your causal inferences from observational data
por: Raymaekers, Koen, et al.
Publicado: (2020)

Confounding and regression adjustment in difference‐in‐differences studies
por: Zeldow, Bret, et al.
Publicado: (2021)

An algorithm using administrative data to measure adverse childhood experiences (ADM‐ACE)
por: Henkhaus, Laura E., et al.
Publicado: (2022)

Natural language processing to identify social determinants of health in Alzheimer's disease and related dementia from electronic health records
por: Wu, Wenbo, et al.
Publicado: (2023)

When logic fails
por: Phan, Justin, et al.
Publicado: (2023)

Reflection on modern methods: when is a stepped-wedge cluster randomized trial a good study design choice?
por: Hemming, Karla, et al.
Publicado: (2020)

Flux balance analysis accounting for metabolite dilution
por: Benyamini, Tomer, et al.
Publicado: (2010)

DISTILLER: a data integration framework to reveal condition dependency of complex regulons in Escherichia coli
por: Lemmens, Karen, et al.
Publicado: (2009)

Interventions to increase the reporting of occupational diseases by physicians: a Cochrane systematic review
por: Curti, Stefania, et al.
Publicado: (2016)

Interrupted time series regression for the evaluation of public health interventions: a tutorial
por: Bernal, James Lopez, et al.
Publicado: (2017)

Efficacy of Oral Nutritional Supplements in Patients Undergoing Surgical Intervention for Hip Fracture
por: Ashkenazi, Itay, et al.
Publicado: (2022)

Effect of the COVID‐19 pandemic on surgical oncology practice—Results of an SSO survey
por: Gribkova, Yelizaveta, et al.
Publicado: (2022)

Exploring regression dilution bias using repeat measurements of 2858 variables in ≤49 000 UK Biobank participants
por: Rutter, Charlotte E, et al.
Publicado: (2023)

Tixagevimab and Cilgavimab (Evusheld) as Pre-exposure Prophylaxis for COVID-19 in Patients With Inflammatory Bowel Disease: A Propensity Matched Cohort Study
por: Desai, Aakash, et al.
Publicado: (2023)

Reflection on modern methods: calculating a sample size for a repeatability sub-study to correct for measurement error in a single continuous exposure
por: Morgan, Katy E, et al.
Publicado: (2019)

Reflection on modern methods: generalized linear models for prognosis and intervention—theory, practice and implications for machine learning
por: Arnold, Kellyn F, et al.
Publicado: (2020)

ARE INTERVENTIONS OUTSIDE THE WORKPLACE TO REDUCE SEDENTARY BEHAVIOR IN ADULTS EFFECTIVE? - A COCHRANE REVIEW SUMMARY WITH COMMENTARY
por: LEVACK, William
Publicado: (2023)

Encorafenib and Binimetinib Combination Therapy in Metastatic Melanoma
por: Davis, Jessica, et al.
Publicado: (2022)

What are the effects of exercise interventions for preventing falls in older people living in the community? - A Cochrane Review summary with commentary
por: Fusco, Augusto
Publicado: (2019)

Evaluating feasibility and satisfaction of a group intervention for mild cognitive impairment in older age bipolar disorder: “Brain train”
por: Schouws, Sigfried N. T. M., et al.
Publicado: (2021)

Exploring and mitigating potential bias when genetic instrumental variables are associated with multiple non-exposure traits in Mendelian randomization
por: Yang, Qian, et al.
Publicado: (2022)

Methods to determine the quality of acid oils and fatty acid distillates used in animal feeding
por: Varona, Elisa, et al.
Publicado: (2021)

Are multifactorial and multiple component interventions effective in preventing falls in older people living in the community? A Cochrane Review summary with commentary
por: Fusco, Augusto
Publicado: (2019)

Role of Luspatercept in the Management of Lower-Risk Myelodysplastic Syndromes
por: Tinsley-Vance, Sara M., et al.
Publicado: (2023)

Are environmental and behavioral interventions effective in reducing physical activity limitation and preventing falls in the visually impaired older individuals? - A Cochrane Review summary with commentary
por: Sindel, Dilsad, et al.
Publicado: (2021)

What is the difference between missing completely at random and missing at random?
por: Bhaskaran, Krishnan, et al.
Publicado: (2014)

What are the efficacy and safety of pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic kidney disease stages 3-5D? - A Cochrane Review summary with commentary
por: Iolascon, Giovanni, et al.
Publicado: (2022)

TICA: Transcriptional Interaction and Coregulation Analyzer
por: Perna, Stefano, et al.
Publicado: (2018)

Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?
por: Delorme-Axford, Elizabeth, et al.
Publicado: (2020)

Special Focus: Bioinformatics
por: Nawrocki, Eric P., et al.
Publicado: (2013)

Key considerations for designing, conducting and analysing a cluster randomized trial
por: Hemming, Karla, et al.
Publicado: (2023)

A Multidisciplinary Approach to Expedite Surgical Hip Fracture Care
por: Burton, Alex, et al.
Publicado: (2020)

Is There a Role for CT Pan-Scans in the Initial Workup of Fragility Fracture Patients?
por: Lepkowsky, Eric, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rtnvbu2l39eartuk64sro8pi54