tRNA methylation resolves codon usage bias at the limit of cell viability

Codon usage of each genome is closely correlated with the abundance of tRNA isoacceptors. How codon usage bias is resolved by tRNA post-transcriptional modifications is largely unknown. Here we demonstrate that the N(1)-methylation of guanosine at position 37 (m(1)G37) on the 3′-side of the anticodo...

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Detalles Bibliográficos
Autores principales: Masuda, Isao, Yamaki, Yuka, Detroja, Rajesh, Tagore, Somnath, Moore, Henry, Maharjan, Sunita, Nakano, Yuko, Christian, Thomas, Matsubara, Ryuma, Lowe, Todd M., Frenkel-Morgenstern, Milana, Hou, Ya-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643105/
https://www.ncbi.nlm.nih.gov/pubmed/36288695
http://dx.doi.org/10.1016/j.celrep.2022.111539

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