Site-selective oral delivery of therapeutic antibodies to the inflamed colon via a folic acid-grafted organic/inorganic hybrid nanocomposite system

This study aimed to develop a pH-responsive folic acid-grafted organic/inorganic hybrid nanocomposite system for site-selective oral delivery of therapeutic antibodies. A folic acid-grafted aminoclay (FA-AC) was prepared via an in situ sol‒gel method. Then, a drug-loaded nanocomplex was prepared via...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hoon, Song, Jae Geun, Han, Hyo-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643170/
https://www.ncbi.nlm.nih.gov/pubmed/36386471
http://dx.doi.org/10.1016/j.apsb.2022.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643170/
https://www.ncbi.nlm.nih.gov/pubmed/36386471
http://dx.doi.org/10.1016/j.apsb.2022.06.006

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