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Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo

Colorectal cancer (CRC) is the second most common cause of cancer-related death in the world. The pro-viral integration site for Moloney murine leukemia virus 1 (PIM1) is a proto-oncogene and belongs to the serine/threonine kinase family, which are involved in cell proliferation, migration, and apop...

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Detalles Bibliográficos
Autores principales:	Yin, Fanxiang, Zhao, Ran, Gorja, Dhilli Rao, Fu, Xiaorong, Lu, Ning, Huang, Hai, Xu, Beibei, Chen, Hanyong, Shim, Jung-Hyun, Liu, Kangdong, Li, Zhi, Laster, Kyle Vaughn, Dong, Zigang, Lee, Mee-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643289/ https://www.ncbi.nlm.nih.gov/pubmed/36386480 http://dx.doi.org/10.1016/j.apsb.2022.07.005

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