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The first mitotic division of human embryos is highly error prone
Human beings are made of ~50 trillion cells which arise from serial mitotic divisions of a single cell - the fertilised egg. Remarkably, the early human embryo is often chromosomally abnormal, and many are mosaic, with the karyotype differing from one cell to another. Mosaicism presumably arises fro...
Autores principales: | Currie, Cerys E., Ford, Emma, Benham Whyte, Lucy, Taylor, Deborah M., Mihalas, Bettina P., Erent, Muriel, Marston, Adele L., Hartshorne, Geraldine M., McAinsh, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643329/ https://www.ncbi.nlm.nih.gov/pubmed/36347869 http://dx.doi.org/10.1038/s41467-022-34294-6 |
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