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A mechanistic mathematical model of initiation and malignant transformation in sporadic vestibular schwannoma
BACKGROUND: A vestibular schwannoma (VS) is a relatively rare, benign tumour of the eighth cranial nerve, often involving alterations to the gene NF2. Previous mathematical models of schwannoma incidence have not attempted to account for alterations in specific genes, and could not distinguish betwe...
Autores principales: | Paterson, Chay, Bozic, Ivana, Smith, Miriam J., Hoad, Xanthe, Evans, D. Gareth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643471/ https://www.ncbi.nlm.nih.gov/pubmed/36097176 http://dx.doi.org/10.1038/s41416-022-01955-8 |
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