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A mechanistic mathematical model of initiation and malignant transformation in sporadic vestibular schwannoma

BACKGROUND: A vestibular schwannoma (VS) is a relatively rare, benign tumour of the eighth cranial nerve, often involving alterations to the gene NF2. Previous mathematical models of schwannoma incidence have not attempted to account for alterations in specific genes, and could not distinguish betwe...

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Detalles Bibliográficos
Autores principales: Paterson, Chay, Bozic, Ivana, Smith, Miriam J., Hoad, Xanthe, Evans, D. Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643471/
https://www.ncbi.nlm.nih.gov/pubmed/36097176
http://dx.doi.org/10.1038/s41416-022-01955-8

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