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Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats

Hypertension affects 1 in 3 adults in the United States and leads to left ventricular (LV) concentric hypertrophy, interstitial fibrosis, and increased stiffness. The treatment of cardiac fibrosis remains challenging and empiric. Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid t...

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Detalles Bibliográficos
Autores principales: Gharraee, Nazli, Wang, Zhan, Pflum, Adam, Medina-Hernandez, Danielle, Herrington, David, Zhu, Xuewei, Meléndez, Giselle C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643491/
https://www.ncbi.nlm.nih.gov/pubmed/36206854
http://dx.doi.org/10.1016/j.jlr.2022.100292