Sensitisation of cancer cells to radiotherapy by serine and glycine starvation

BACKGROUND: Cellular metabolism is an integral component of cellular adaptation to stress, playing a pivotal role in the resistance of cancer cells to various treatment modalities, including radiotherapy. In response to radiotherapy, cancer cells engage antioxidant and DNA repair mechanisms which mi...

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Detalles Bibliográficos
Autores principales: Falcone, Mattia, Uribe, Alejandro Huerta, Papalazarou, Vasileios, Newman, Alice C., Athineos, Dimitris, Stevenson, Katrina, Sauvé, Charles-Etienne Gabriel, Gao, Yajing, Kim, Jin K., Del Latto, Michael, Kierstead, Maria, Wu, Chao, Smith, J. Joshua, Romesser, Paul B., Chalmers, Anthony J., Blyth, Karen, Maddocks, Oliver D. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643498/
https://www.ncbi.nlm.nih.gov/pubmed/36115879
http://dx.doi.org/10.1038/s41416-022-01965-6

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