Cargando…
Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma
The association between neurocognitive function (NCF) impairment and brain cortical functional connectivity in glioma patients remains unclear. The correlations between brain oscillatory activity or functional connectivity and NCF measured by the Wechsler Adult Intelligence Scale full-scale intellig...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643499/ https://www.ncbi.nlm.nih.gov/pubmed/36347905 http://dx.doi.org/10.1038/s41598-022-22493-6 |
_version_ | 1784826541402750976 |
---|---|
author | Ueda, Masaya Usami, Kiyohide Yamao, Yukihiro Yamawaki, Rie Umaba, Chinatsu Liang, Nan Nankaku, Manabu Mineharu, Yohei Honda, Masayuki Hitomi, Takefumi Ikeguchi, Ryosuke Ikeda, Akio Miyamoto, Susumu Matsuda, Shuichi Arakawa, Yoshiki |
author_facet | Ueda, Masaya Usami, Kiyohide Yamao, Yukihiro Yamawaki, Rie Umaba, Chinatsu Liang, Nan Nankaku, Manabu Mineharu, Yohei Honda, Masayuki Hitomi, Takefumi Ikeguchi, Ryosuke Ikeda, Akio Miyamoto, Susumu Matsuda, Shuichi Arakawa, Yoshiki |
author_sort | Ueda, Masaya |
collection | PubMed |
description | The association between neurocognitive function (NCF) impairment and brain cortical functional connectivity in glioma patients remains unclear. The correlations between brain oscillatory activity or functional connectivity and NCF measured by the Wechsler Adult Intelligence Scale full-scale intelligence quotient scores (WAIS FSIQ), the Wechsler Memory Scale-revised general memory scores (WMS-R GM), and the Western aphasia battery aphasia quotient scores (WAB AQ) were evaluated in 18 patients with left frontal glioma using resting-state electroencephalography (EEG). Current source density (CSD) and lagged phase synchronization (LPS) were analyzed using exact low-resolution electromagnetic tomography (eLORETA). Although 2 and 2 patients scored in the borderline range of WAIS FSIQ and WMS-R GM, respectively, the mean WAIS FSIQ, WMS-R GM, and WAB AQ values of all patients were within normal limits, and none had aphasia. In the correlation analysis, lower WMS-R GM was associated with a higher LPS value between the right anterior prefrontal cortex and the left superior parietal lobule in the beta1 band (13–20 Hz, R = − 0.802, P = 0.012). These findings suggest that LPS evaluated by scalp EEG is associated with memory function in patients with left frontal glioma and mild NCF disorders. |
format | Online Article Text |
id | pubmed-9643499 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-96434992022-11-15 Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma Ueda, Masaya Usami, Kiyohide Yamao, Yukihiro Yamawaki, Rie Umaba, Chinatsu Liang, Nan Nankaku, Manabu Mineharu, Yohei Honda, Masayuki Hitomi, Takefumi Ikeguchi, Ryosuke Ikeda, Akio Miyamoto, Susumu Matsuda, Shuichi Arakawa, Yoshiki Sci Rep Article The association between neurocognitive function (NCF) impairment and brain cortical functional connectivity in glioma patients remains unclear. The correlations between brain oscillatory activity or functional connectivity and NCF measured by the Wechsler Adult Intelligence Scale full-scale intelligence quotient scores (WAIS FSIQ), the Wechsler Memory Scale-revised general memory scores (WMS-R GM), and the Western aphasia battery aphasia quotient scores (WAB AQ) were evaluated in 18 patients with left frontal glioma using resting-state electroencephalography (EEG). Current source density (CSD) and lagged phase synchronization (LPS) were analyzed using exact low-resolution electromagnetic tomography (eLORETA). Although 2 and 2 patients scored in the borderline range of WAIS FSIQ and WMS-R GM, respectively, the mean WAIS FSIQ, WMS-R GM, and WAB AQ values of all patients were within normal limits, and none had aphasia. In the correlation analysis, lower WMS-R GM was associated with a higher LPS value between the right anterior prefrontal cortex and the left superior parietal lobule in the beta1 band (13–20 Hz, R = − 0.802, P = 0.012). These findings suggest that LPS evaluated by scalp EEG is associated with memory function in patients with left frontal glioma and mild NCF disorders. Nature Publishing Group UK 2022-11-08 /pmc/articles/PMC9643499/ /pubmed/36347905 http://dx.doi.org/10.1038/s41598-022-22493-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Ueda, Masaya Usami, Kiyohide Yamao, Yukihiro Yamawaki, Rie Umaba, Chinatsu Liang, Nan Nankaku, Manabu Mineharu, Yohei Honda, Masayuki Hitomi, Takefumi Ikeguchi, Ryosuke Ikeda, Akio Miyamoto, Susumu Matsuda, Shuichi Arakawa, Yoshiki Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma |
title | Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma |
title_full | Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma |
title_fullStr | Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma |
title_full_unstemmed | Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma |
title_short | Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma |
title_sort | correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643499/ https://www.ncbi.nlm.nih.gov/pubmed/36347905 http://dx.doi.org/10.1038/s41598-022-22493-6 |
work_keys_str_mv | AT uedamasaya correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT usamikiyohide correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT yamaoyukihiro correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT yamawakirie correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT umabachinatsu correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT liangnan correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT nankakumanabu correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT mineharuyohei correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT hondamasayuki correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT hitomitakefumi correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT ikeguchiryosuke correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT ikedaakio correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT miyamotosusumu correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT matsudashuichi correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma AT arakawayoshiki correlationbetweenbrainfunctionalconnectivityandneurocognitivefunctioninpatientswithleftfrontalglioma |