Spectroscopic characterization and in vitro studies of biological activity of bradykinin derivatives

Eleven multiple analogs of bradykinin—a peptide that is a natural ligand of B1 and B2 receptors but does not bind or activate the B1 receptor unless Arg(9) is removed from the sequence by the action of carboxypeptidase N—were synthesized. Their biological activity was examined on T-REx cell lines ex...

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Detalles Bibliográficos
Autores principales: Proniewicz, Edyta, Burnat, Grzegorz, Domin, Helena, Iłowska, Emilia, Roman, Adam, Prahl, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643506/
https://www.ncbi.nlm.nih.gov/pubmed/36348016
http://dx.doi.org/10.1038/s41598-022-23448-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643506/
https://www.ncbi.nlm.nih.gov/pubmed/36348016
http://dx.doi.org/10.1038/s41598-022-23448-7

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