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Spectroscopic characterization and in vitro studies of biological activity of bradykinin derivatives
Eleven multiple analogs of bradykinin—a peptide that is a natural ligand of B1 and B2 receptors but does not bind or activate the B1 receptor unless Arg(9) is removed from the sequence by the action of carboxypeptidase N—were synthesized. Their biological activity was examined on T-REx cell lines ex...
Autores principales: | Proniewicz, Edyta, Burnat, Grzegorz, Domin, Helena, Iłowska, Emilia, Roman, Adam, Prahl, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643506/ https://www.ncbi.nlm.nih.gov/pubmed/36348016 http://dx.doi.org/10.1038/s41598-022-23448-7 |
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