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Evaluation of auditory system in obstructive sleep apnea patients
OBJECTIVES: Obstructive sleep apnea (OSA) has been associated with auditory dysfunction both to the cochlear and higher auditory pathways. However, available literatures presented conflicting results. We aimed to study the impact of OSA severity and their polysomnography parameters on hearing functi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643906/ https://www.ncbi.nlm.nih.gov/pubmed/36350365 http://dx.doi.org/10.1007/s00405-022-07711-1 |
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author | Lim, Chee Chean Ahmad, Tengku Ezulia Binti Tengku Nun Sawali, Halimuddin Bin Afandi, Ahmad Nordin Bin Paniselvam, Vinota Bernard, Merlinda W. Narayanan, Prepageran Bakar, Mohd Zukiflee Bin Abu |
author_facet | Lim, Chee Chean Ahmad, Tengku Ezulia Binti Tengku Nun Sawali, Halimuddin Bin Afandi, Ahmad Nordin Bin Paniselvam, Vinota Bernard, Merlinda W. Narayanan, Prepageran Bakar, Mohd Zukiflee Bin Abu |
author_sort | Lim, Chee Chean |
collection | PubMed |
description | OBJECTIVES: Obstructive sleep apnea (OSA) has been associated with auditory dysfunction both to the cochlear and higher auditory pathways. However, available literatures presented conflicting results. We aimed to study the impact of OSA severity and their polysomnography parameters on hearing function. MATERIALS AND METHODS: A total of 44 patients were included after evaluation for sleep disorders and were divided into four groups in accordance with apnea–hypopnea index (AHI). Pure tone audiometry (PTA), distortion product otoacoustic emission (DPOAE) and auditory brainstem response (ABR) were compared in commensurate with the severity of AHI. Polysomnography oximetry parameters of oxygen desaturation index, mean SPO2, minimum SPO2 and percent SPO2 < 90% were correlated with their respective PTA, DPOAE and ABR results. RESULTS: There was no significant change in the PTA, DPOAE and ABR results in connection with AHI severity. However, we found significant correlations between mean SPO2 and percent SPO2 < 90% with ABR wave I, III and V absolute latencies. Minimum SPO2 was also significantly correlated with wave III peak latency changes. CONCLUSIONS: Mean SPO2, percent SPO2 < 90% and minimum SPO2 could be key prognostic indicators of central auditory dysfunction in OSA patients. These parameters should be explored further as indicators of OSA severity rather than utilizing AHI alone. The hypoxic burden derived could be a better predictor of auditory function abnormalities rather than one derived from AHI. |
format | Online Article Text |
id | pubmed-9643906 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-96439062022-11-14 Evaluation of auditory system in obstructive sleep apnea patients Lim, Chee Chean Ahmad, Tengku Ezulia Binti Tengku Nun Sawali, Halimuddin Bin Afandi, Ahmad Nordin Bin Paniselvam, Vinota Bernard, Merlinda W. Narayanan, Prepageran Bakar, Mohd Zukiflee Bin Abu Eur Arch Otorhinolaryngol Otology OBJECTIVES: Obstructive sleep apnea (OSA) has been associated with auditory dysfunction both to the cochlear and higher auditory pathways. However, available literatures presented conflicting results. We aimed to study the impact of OSA severity and their polysomnography parameters on hearing function. MATERIALS AND METHODS: A total of 44 patients were included after evaluation for sleep disorders and were divided into four groups in accordance with apnea–hypopnea index (AHI). Pure tone audiometry (PTA), distortion product otoacoustic emission (DPOAE) and auditory brainstem response (ABR) were compared in commensurate with the severity of AHI. Polysomnography oximetry parameters of oxygen desaturation index, mean SPO2, minimum SPO2 and percent SPO2 < 90% were correlated with their respective PTA, DPOAE and ABR results. RESULTS: There was no significant change in the PTA, DPOAE and ABR results in connection with AHI severity. However, we found significant correlations between mean SPO2 and percent SPO2 < 90% with ABR wave I, III and V absolute latencies. Minimum SPO2 was also significantly correlated with wave III peak latency changes. CONCLUSIONS: Mean SPO2, percent SPO2 < 90% and minimum SPO2 could be key prognostic indicators of central auditory dysfunction in OSA patients. These parameters should be explored further as indicators of OSA severity rather than utilizing AHI alone. The hypoxic burden derived could be a better predictor of auditory function abnormalities rather than one derived from AHI. Springer Berlin Heidelberg 2022-11-09 2023 /pmc/articles/PMC9643906/ /pubmed/36350365 http://dx.doi.org/10.1007/s00405-022-07711-1 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Otology Lim, Chee Chean Ahmad, Tengku Ezulia Binti Tengku Nun Sawali, Halimuddin Bin Afandi, Ahmad Nordin Bin Paniselvam, Vinota Bernard, Merlinda W. Narayanan, Prepageran Bakar, Mohd Zukiflee Bin Abu Evaluation of auditory system in obstructive sleep apnea patients |
title | Evaluation of auditory system in obstructive sleep apnea patients |
title_full | Evaluation of auditory system in obstructive sleep apnea patients |
title_fullStr | Evaluation of auditory system in obstructive sleep apnea patients |
title_full_unstemmed | Evaluation of auditory system in obstructive sleep apnea patients |
title_short | Evaluation of auditory system in obstructive sleep apnea patients |
title_sort | evaluation of auditory system in obstructive sleep apnea patients |
topic | Otology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643906/ https://www.ncbi.nlm.nih.gov/pubmed/36350365 http://dx.doi.org/10.1007/s00405-022-07711-1 |
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