Cargando…

Development of D-α-Tocopherol polyethylene glycol 1000 succinate fabricated nanostructural lipid carrier of sorafenib tosylate for metastatic colorectal targeting application: Stability, physical characterization, cytotoxicity, and apoptotic studies against SW48 cells PTEN

The study aimed to create D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS) nanostructured lipid carriers (NLC) of sorafenib tosylate (ST) as lymphatic delivery systems (LDDS) to fight Metastatic colorectal cancer. Initially, ST-SLN, ST-NLC, and ST-LNE were formulated considering oleic acid (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhattacharya, Sankha, Sharma, Satyam, Prajapati, Bhupendra G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644033/ https://www.ncbi.nlm.nih.gov/pubmed/36387097 http://dx.doi.org/10.3389/fonc.2022.990841

Ejemplares similares

Comparison of α-Tocopherol, α-Tocopherol Acetate, and α-Tocopheryl Polyethylene Glycol Succinate 1000 Absorption by Caco-2 TC7 Intestinal Cells
por: Cuerq, Charlotte, et al.
Publicado: (2020)

Rp-HPLC Determination of Quercetin in a Novel D-α-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma
por: Ahmed, Osama A. A., et al.
Publicado: (2021)

Codelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles
por: Chen, Dazhong, et al.
Publicado: (2018)

D-α-tocopherol polyethylene glycol succinate-based derivative nanoparticles as a novel carrier for paclitaxel delivery
por: Wu, Yupei, et al.
Publicado: (2015)

Multiple Functions of D-α-Tocopherol Polyethylene Glycol 1000 Succinate (TPGS) as Curcumin Nanoparticle Stabilizer: In Vivo Kinetic Profile and Anti-Ulcerative Colitis Analysis in Animal Model
por: Rachmawati, Heni, et al.
Publicado: (2017)

D-α-tocopherol polyethylene glycol 1000 succinate-modified liposomes with an siRNA corona confer enhanced cellular uptake and targeted delivery of doxorubicin via tumor priming
por: Tan, Xi, et al.
Publicado: (2019)

Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions
por: Sun, Deqing, et al.
Publicado: (2014)

Biological fate and interaction with cytochromes P450 of the nanocarrier material, d-α-tocopheryl polyethylene glycol 1000 succinate
por: Ren, Tianming, et al.
Publicado: (2022)

Bactericidal activity of propylene glycol, glycerine, polyethylene glycol 400, and polyethylene glycol 1000 against selected microorganisms
por: Nalawade, Triveni Mohan, et al.
Publicado: (2015)

Therapeutic Potential of Methotrexate-Loaded Superparamagnetic Iron Oxide Nanoparticles Coated with Poly(lactic-co-glycolic acid) and Polyethylene Glycol against Breast Cancer: Development, Characterization, and Comprehensive In Vitro Investigation
por: Bhattacharya, Sankha, et al.
Publicado: (2023)

Optimized vinpocetine-loaded vitamin E D-α-tocopherol polyethylene glycol 1000 succinate-alpha lipoic acid micelles as a potential transdermal drug delivery system: in vitro and ex vivo studies
por: Ahmed, Osama AA, et al.
Publicado: (2018)

Nanoparticles of Poly(Lactide-Co-Glycolide)-d-a-Tocopheryl Polyethylene Glycol 1000 Succinate Random Copolymer for Cancer Treatment
por: Ma, Yuandong, et al.
Publicado: (2010)

Characterization, in Vivo and in Vitro Evaluation of Solid Dispersion of Curcumin Containing d-α-Tocopheryl Polyethylene Glycol 1000 Succinate and Mannitol
por: Song, Im-Sook, et al.
Publicado: (2016)

Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy
por: Chu, Qiuchen, et al.
Publicado: (2016)

Development and evaluation of vitamin E d-α-tocopheryl polyethylene glycol 1000 succinate-mixed polymeric phospholipid micelles of berberine as an anticancer nanopharmaceutical
por: Shen, Roger, et al.
Publicado: (2016)

Topical anesthesia therapy using lidocaine-loaded nanostructured lipid carriers: tocopheryl polyethylene glycol 1000 succinate-modified transdermal delivery system
por: Zhao, Xiangju, et al.
Publicado: (2018)

Fabrication and in vitro/in vivo evaluation of amorphous andrographolide nanosuspensions stabilized by d-α-tocopheryl polyethylene glycol 1000 succinate/sodium lauryl sulfate
por: Qiao, Hongzhi, et al.
Publicado: (2017)

Nucleic Acid Delivery with α-Tocopherol-Polyethyleneimine-Polyethylene Glycol Nanocarrier System
por: Hossian, A K M Nawshad, et al.
Publicado: (2020)

Iron Transport Tocopheryl Polyethylene Glycol Succinate in Animal Health and Diseases
por: Srivastava, Ajay, et al.
Publicado: (2019)

Triphenylphosphonium and D-α-tocopheryl polyethylene glycol 1000 succinate-modified, tanshinone IIA-loaded lipid-polymeric nanocarriers for the targeted therapy of myocardial infarction
por: Zhang, Shouwen, et al.
Publicado: (2018)

Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles
por: Hao, Jifu, et al.
Publicado: (2017)

d-a-Tocopheryl Polyethylene Glycol 1000 Succinate and a small-molecule Survivin suppressant synergistically induce apoptosis in SKBR3 breast cancer cells
por: Neophytou, Christiana M., et al.
Publicado: (2019)

Resveratrol-Loaded Polymeric Nanoparticles: The Effects of D-α-Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS) on Physicochemical and Biological Properties against Breast Cancer In Vitro and In Vivo
por: Cavalcante de Freitas, Paulo George, et al.
Publicado: (2023)

Design of vitamin E d-α-Tocopheryl Polyethylene Glycol 1000 Succinate-Emulsified Poly (D,L–Lactide–co-Glycolide) Nanoparticles: Influence of Duration of Ultrasonication Energy
por: Şengel, CT, et al.
Publicado: (2011)

Polyethylene glycol triggers the anti-cancer impact of curcumin nanoparticles in sw-1736 thyroid cancer cells
por: Hosseinzadeh, Simzar, et al.
Publicado: (2021)

Unveiling the therapeutic potential of cabozantinib-loaded poly D,L-lactic-co-glycolic acid and polysarcosine nanoparticles in inducing apoptosis and cytotoxicity in human HepG2 hepatocellular carcinoma cell lines and in vivo anti-tumor activity in SCID female mice
por: Bhattacharya, Sankha, et al.
Publicado: (2023)

Impact of Crystal Habit on the Dissolution Rate and In Vivo Pharmacokinetics of Sorafenib Tosylate
por: Phan, Chi Uyen, et al.
Publicado: (2021)

Recent developments in d-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy
por: Tan, Songwei, et al.
Publicado: (2017)

Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo
por: Zhang, Youwen, et al.
Publicado: (2017)

Poloxamer-188 and d-α-Tocopheryl Polyethylene Glycol Succinate (TPGS-1000) Mixed Micelles Integrated Orodispersible Sublingual Films to Improve Oral Bioavailability of Ebastine; In Vitro and In Vivo Characterization
por: Islam, Nayyer, et al.
Publicado: (2021)

Preparation, in vitro and in vivo evaluation of polymeric nanoparticles based on hyaluronic acid-poly(butyl cyanoacrylate) and D-alpha-tocopheryl polyethylene glycol 1000 succinate for tumor-targeted delivery of morin hydrate
por: Abbad, Sarra, et al.
Publicado: (2015)

DACHPt-Loaded Nanoparticles Self-assembled from Biodegradable Dendritic Copolymer Polyglutamic Acid-b-D-α-Tocopheryl Polyethylene Glycol 1000 Succinate for Multidrug Resistant Lung Cancer Therapy
por: Tsai, Hsiang-I, et al.
Publicado: (2018)

Structural Polymorphism of Sorafenib Tosylate as a Key Factor in Its Solubility Differentiation
por: Wiergowska, Gabriela, et al.
Publicado: (2021)

Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix
por: Guo, Yang, et al.
Publicado: (2017)

Radioprotective properties of tocopherol succinate against ionizing radiation in mice
por: Singh, Vijay K., et al.
Publicado: (2013)

Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for siRNA targeting HIF-1α for nasopharyngeal carcinoma therapy
por: Chen, Yuhan, et al.
Publicado: (2015)

Synthesis, Colloidal Characterization and Targetability of Phenylboronic Acid Functionalized α-Tocopheryl Polyethylene Glycol Succinate in Cancer Cells
por: Tiwari, Sanjay, et al.
Publicado: (2020)

Redox-responsive F127-folate/F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate/P123 mixed micelles loaded with paclitaxel for the reversal of multidrug resistance in tumors
por: Lin, Jing, et al.
Publicado: (2018)

Synthesis and Characterization of Polyethylene Glycol-Grafted Photoreactive Polyethylene Glycols for Antibiofouling Applications
por: Othman, Mahmoud H., et al.
Publicado: (2022)

Development of Formulation Methods and Physical Characterization of Injectable Sodium Selenite Nanoparticles for the Delivery of Sorafenib tosylate
por: Moni, Sivakumar S., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_falnft60kfn6gsdf4l1df88o4q