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Glial cells and neurologic autoimmune disorders

Neurologic autoimmune disorders affect people’s physical and mental health seriously. Glial cells, as an important part of the nervous system, play a vital role in the occurrence of neurologic autoimmune disorders. Glial cells can be hyperactivated in the presence of autoantibodies or pathological c...

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Detalles Bibliográficos
Autores principales: Li, Zhao-Qing, Li, Tong-Xin, Tian, Miao, Ren, Ze-Sheng, Yuan, Chen-Yi, Yang, Rui-Kun, Shi, Su-Juan, Li, Hui, Kou, Zhen-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644207/
https://www.ncbi.nlm.nih.gov/pubmed/36385950
http://dx.doi.org/10.3389/fncel.2022.1028653
Descripción
Sumario:Neurologic autoimmune disorders affect people’s physical and mental health seriously. Glial cells, as an important part of the nervous system, play a vital role in the occurrence of neurologic autoimmune disorders. Glial cells can be hyperactivated in the presence of autoantibodies or pathological changes, to influence neurologic autoimmune disorders. This review is mainly focused on the roles of glial cells in neurologic autoimmune disorders and the influence of autoantibodies produced by autoimmune disorders on glial cells. We speculate that the possibility of glial cells might be a novel way for the investigation and therapy of neurologic autoimmune disorders.