Transcriptomics, regulatory syntax, and enhancer identification in mesoderm-induced ESCs at single-cell resolution

Embryonic stem cells (ESCs) can adopt lineage-specific gene-expression programs by stepwise exposure to defined factors, resulting in the generation of functional cell types. Bulk and single-cell-based assays were employed to catalog gene expression, histone modifications, chromatin conformation, an...

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Detalles Bibliográficos
Autores principales: Khateb, Mamduh, Perovanovic, Jelena, Ko, Kyung Dae, Jiang, Kan, Feng, Xuesong, Acevedo-Luna, Natalia, Chal, Jérome, Ciuffoli, Veronica, Genzor, Pavol, Simone, James, Haase, Astrid D., Pourquié, Olivier, Dell’Orso, Stefania, Sartorelli, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644345/
https://www.ncbi.nlm.nih.gov/pubmed/35977485
http://dx.doi.org/10.1016/j.celrep.2022.111219

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