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Hyperglycemic Conditions Promote Rac1-Mediated Serine536 Phosphorylation of p65 Subunit of NFκB (RelA) in Pancreatic Beta Cells

BACKGROUND/AIMS: We recently reported increased phosphorylation (at S536) of the p65 subunit of NFκB (Rel A) in pancreatic beta (INS-1 832/13) cells following exposure to hyperglycemic (HG) conditions. We also demonstrated that HG-induced S536 phosphorylation of p65 is downstream to the regulatory e...

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Detalles Bibliográficos
Autores principales:	Kowluru, Anjaneyulu, Gamage, Suhadinie, Hali, Mirabela, Gleason, Noah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644397/ https://www.ncbi.nlm.nih.gov/pubmed/35981264 http://dx.doi.org/10.33594/000000557

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