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Peptides as Pharmacological Carriers to the Brain: Promises, Shortcomings and Challenges
[Image: see text] Central nervous system (CNS) diseases are among the most difficult to treat, mainly because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach the brain at concentrations adequate to exert a pharmacological activity. The obstacle posed by the BBB...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644402/ https://www.ncbi.nlm.nih.gov/pubmed/36174227 http://dx.doi.org/10.1021/acs.molpharmaceut.2c00523 |