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Gut fungi enhances immunosuppressive function of myeloid-derived suppressor cells by activating PKM2-dependent glycolysis to promote colorectal tumorigenesis

BACKGROUND: Accumulating evidence implicates that gut fungi are associated with the pathogenesis of colorectal cancer (CRC). Our previous study has revealed that Candida tropicalis (C. tropicalis) promotes colorectal tumorigenesis by enhancing immunosuppressive function of myeloid-derived suppressor...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhiyong, Zheng, Yaojun, Chen, Ying, Yin, Yuxin, Chen, Yuxi, Chen, Qianyu, Hou, Yayi, Shen, Sunan, Lv, Mingming, Wang, Tingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644472/ https://www.ncbi.nlm.nih.gov/pubmed/36348389 http://dx.doi.org/10.1186/s40164-022-00334-6

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