mir-145-5p is a suppressor of colorectal cancer at early stage, while promotes colorectal cancer metastasis at late stage through regulating AKT signaling evoked EMT-mediated anoikis

BACKGROUND: miR-145-5P is generally considered as a tumor suppressor at early stage of colorectal cancer, but up-regulation occurs in the progressive and later stages which is associated with metastasis, indicating miR-145-5p may play dual role in colorectal cancer (CRC). To explore the detailed mec...

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Detalles Bibliográficos
Autores principales: Cheng, Xianshuo, Shen, Tao, Liu, Ping, Fang, Shaojun, Yang, Zhibin, Li, Yunfeng, Dong, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644492/
https://www.ncbi.nlm.nih.gov/pubmed/36348305
http://dx.doi.org/10.1186/s12885-022-10182-6

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