HiTIMED: hierarchical tumor immune microenvironment epigenetic deconvolution for accurate cell type resolution in the tumor microenvironment using tumor-type-specific DNA methylation data

BACKGROUND: Cellular compositions of solid tumor microenvironments are heterogeneous, varying across patients and tumor types. High-resolution profiling of the tumor microenvironment cell composition is crucial to understanding its biological and clinical implications. Previously, tumor microenviron...

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Detalles Bibliográficos
Autores principales: Zhang, Ze, Wiencke, John K., Kelsey, Karl T., Koestler, Devin C., Christensen, Brock C., Salas, Lucas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644569/
https://www.ncbi.nlm.nih.gov/pubmed/36348337
http://dx.doi.org/10.1186/s12967-022-03736-6

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