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The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen

BACKGROUND: Cutaneous leishmaniasis (CL) is endemic in Yemen. CL displays a spectrum of typical and atypical morphologies yet understudied in the central and southwest regions of Yemen. AIMS AND OBJECTIVES: To identify the typical and atypical clinical phenotypes of CL in the central and southwest r...

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Detalles Bibliográficos
Autores principales: Muthanna, Ahlam M., Malhomme, Helena D., Schwartz, Robert A., Al-Qubati, Yasin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644748/
https://www.ncbi.nlm.nih.gov/pubmed/36386068
http://dx.doi.org/10.4103/ijd.ijd_81_22
Descripción
Sumario:BACKGROUND: Cutaneous leishmaniasis (CL) is endemic in Yemen. CL displays a spectrum of typical and atypical morphologies yet understudied in the central and southwest regions of Yemen. AIMS AND OBJECTIVES: To identify the typical and atypical clinical phenotypes of CL in the central and southwest regions of Yemen. MATERIALS AND METHODS: A survey of 145 patients who visited Prof. Al-Qubati Clinic in Taiz between 2010 and 2015, was conducted. RESULTS: Children and residents of the rural areas were at high risk of exposure to the insect vector. The typical phenotype was single (67%), facial (58%) and ulcerated nodule (35%). Other usual phenotypes were small ulcers (21.4%) and non-ulcerative papules and nodules (21%). Unusual phenotypes constituted 12% of the cohort and included psoriasiform, eczematous, erysipeloid, lupoid, verrucous, large ulcerative, leishmania recidivens, satellite, granulomatous infiltrative and hyperkeratotic plaques. Mucous membrane involvement was evident in 10.6% and was also polymorphic. CONCLUSION: CL has many morphologic patterns in central and southwest regions of Yemen, some are clinically deceptive.