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The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen
BACKGROUND: Cutaneous leishmaniasis (CL) is endemic in Yemen. CL displays a spectrum of typical and atypical morphologies yet understudied in the central and southwest regions of Yemen. AIMS AND OBJECTIVES: To identify the typical and atypical clinical phenotypes of CL in the central and southwest r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644748/ https://www.ncbi.nlm.nih.gov/pubmed/36386068 http://dx.doi.org/10.4103/ijd.ijd_81_22 |
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author | Muthanna, Ahlam M. Malhomme, Helena D. Schwartz, Robert A. Al-Qubati, Yasin A. |
author_facet | Muthanna, Ahlam M. Malhomme, Helena D. Schwartz, Robert A. Al-Qubati, Yasin A. |
author_sort | Muthanna, Ahlam M. |
collection | PubMed |
description | BACKGROUND: Cutaneous leishmaniasis (CL) is endemic in Yemen. CL displays a spectrum of typical and atypical morphologies yet understudied in the central and southwest regions of Yemen. AIMS AND OBJECTIVES: To identify the typical and atypical clinical phenotypes of CL in the central and southwest regions of Yemen. MATERIALS AND METHODS: A survey of 145 patients who visited Prof. Al-Qubati Clinic in Taiz between 2010 and 2015, was conducted. RESULTS: Children and residents of the rural areas were at high risk of exposure to the insect vector. The typical phenotype was single (67%), facial (58%) and ulcerated nodule (35%). Other usual phenotypes were small ulcers (21.4%) and non-ulcerative papules and nodules (21%). Unusual phenotypes constituted 12% of the cohort and included psoriasiform, eczematous, erysipeloid, lupoid, verrucous, large ulcerative, leishmania recidivens, satellite, granulomatous infiltrative and hyperkeratotic plaques. Mucous membrane involvement was evident in 10.6% and was also polymorphic. CONCLUSION: CL has many morphologic patterns in central and southwest regions of Yemen, some are clinically deceptive. |
format | Online Article Text |
id | pubmed-9644748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-96447482022-11-15 The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen Muthanna, Ahlam M. Malhomme, Helena D. Schwartz, Robert A. Al-Qubati, Yasin A. Indian J Dermatol Original Article BACKGROUND: Cutaneous leishmaniasis (CL) is endemic in Yemen. CL displays a spectrum of typical and atypical morphologies yet understudied in the central and southwest regions of Yemen. AIMS AND OBJECTIVES: To identify the typical and atypical clinical phenotypes of CL in the central and southwest regions of Yemen. MATERIALS AND METHODS: A survey of 145 patients who visited Prof. Al-Qubati Clinic in Taiz between 2010 and 2015, was conducted. RESULTS: Children and residents of the rural areas were at high risk of exposure to the insect vector. The typical phenotype was single (67%), facial (58%) and ulcerated nodule (35%). Other usual phenotypes were small ulcers (21.4%) and non-ulcerative papules and nodules (21%). Unusual phenotypes constituted 12% of the cohort and included psoriasiform, eczematous, erysipeloid, lupoid, verrucous, large ulcerative, leishmania recidivens, satellite, granulomatous infiltrative and hyperkeratotic plaques. Mucous membrane involvement was evident in 10.6% and was also polymorphic. CONCLUSION: CL has many morphologic patterns in central and southwest regions of Yemen, some are clinically deceptive. Wolters Kluwer - Medknow 2022 /pmc/articles/PMC9644748/ /pubmed/36386068 http://dx.doi.org/10.4103/ijd.ijd_81_22 Text en Copyright: © 2022 Indian Journal of Dermatology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Muthanna, Ahlam M. Malhomme, Helena D. Schwartz, Robert A. Al-Qubati, Yasin A. The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen |
title | The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen |
title_full | The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen |
title_fullStr | The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen |
title_full_unstemmed | The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen |
title_short | The Clinical Phenotypes of Cutaneous Leishmaniasis in Central and Southwest Regions of Yemen |
title_sort | clinical phenotypes of cutaneous leishmaniasis in central and southwest regions of yemen |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644748/ https://www.ncbi.nlm.nih.gov/pubmed/36386068 http://dx.doi.org/10.4103/ijd.ijd_81_22 |
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