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Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective

Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder affecting 15–20% of children and 1–10% of adults. Staphylococcus aureus (S. aureus) infection is the most frequent complication of AD and is involved in the worsening of the disease. Systemic and topical antibiotics are used i...

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Autores principales: Sharma, Nidhi, Dhar, Sandipan, De, Abhishek, Godse, Kiran, Shankar, D S Krupa, Zawar, Vijay, Girdhar, Mukesh, Shah, Bela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644761/
https://www.ncbi.nlm.nih.gov/pubmed/36386066
http://dx.doi.org/10.4103/ijd.IJD_536_20
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author Sharma, Nidhi
Dhar, Sandipan
De, Abhishek
Godse, Kiran
Shankar, D S Krupa
Zawar, Vijay
Girdhar, Mukesh
Shah, Bela
author_facet Sharma, Nidhi
Dhar, Sandipan
De, Abhishek
Godse, Kiran
Shankar, D S Krupa
Zawar, Vijay
Girdhar, Mukesh
Shah, Bela
author_sort Sharma, Nidhi
collection PubMed
description Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder affecting 15–20% of children and 1–10% of adults. Staphylococcus aureus (S. aureus) infection is the most frequent complication of AD and is involved in the worsening of the disease. Systemic and topical antibiotics are used in the treatment for AD but there are concerns over increasing resistance. Bleach (sodium hypochlorite, NaOCl) baths are an inexpensive, widely accessible, alternative antibiotic treatment that may not worsen antibiotic resistance. Bleach baths are used as adjunctive treatment in AD patients to treat superinfections, although their mechanism of action is not well understood. Balancing safety concerns with efficacious treatment should be important especially for AD where the majority of patients are in pediatrics age groups. Studies available in PubMed databases were included in this review. Most suggested bleach bath improves clinical symptoms of AD and restores surface microbiome by eradicating bacteria, most notably S. aureus. Some studies have noted that this antimicrobial effect has reduced the need for topical corticosteroids. In addition, bleach seems to have strong anti-inflammatory and antipruritic effects. Overall, bleach baths seem to be safe on human skin, without disrupting the epidermal barrier function. The review concluded, although there are some advantages of use of bleach baths, more studies to investigate long-term efficacy and safety of bleach baths are required before fixing its role in the treatment of AD especially in the context of the Indian scenario.
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spelling pubmed-96447612022-11-15 Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective Sharma, Nidhi Dhar, Sandipan De, Abhishek Godse, Kiran Shankar, D S Krupa Zawar, Vijay Girdhar, Mukesh Shah, Bela Indian J Dermatol Review Article Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder affecting 15–20% of children and 1–10% of adults. Staphylococcus aureus (S. aureus) infection is the most frequent complication of AD and is involved in the worsening of the disease. Systemic and topical antibiotics are used in the treatment for AD but there are concerns over increasing resistance. Bleach (sodium hypochlorite, NaOCl) baths are an inexpensive, widely accessible, alternative antibiotic treatment that may not worsen antibiotic resistance. Bleach baths are used as adjunctive treatment in AD patients to treat superinfections, although their mechanism of action is not well understood. Balancing safety concerns with efficacious treatment should be important especially for AD where the majority of patients are in pediatrics age groups. Studies available in PubMed databases were included in this review. Most suggested bleach bath improves clinical symptoms of AD and restores surface microbiome by eradicating bacteria, most notably S. aureus. Some studies have noted that this antimicrobial effect has reduced the need for topical corticosteroids. In addition, bleach seems to have strong anti-inflammatory and antipruritic effects. Overall, bleach baths seem to be safe on human skin, without disrupting the epidermal barrier function. The review concluded, although there are some advantages of use of bleach baths, more studies to investigate long-term efficacy and safety of bleach baths are required before fixing its role in the treatment of AD especially in the context of the Indian scenario. Wolters Kluwer - Medknow 2022 /pmc/articles/PMC9644761/ /pubmed/36386066 http://dx.doi.org/10.4103/ijd.IJD_536_20 Text en Copyright: © 2022 Indian Journal of Dermatology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Sharma, Nidhi
Dhar, Sandipan
De, Abhishek
Godse, Kiran
Shankar, D S Krupa
Zawar, Vijay
Girdhar, Mukesh
Shah, Bela
Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective
title Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective
title_full Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective
title_fullStr Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective
title_full_unstemmed Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective
title_short Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective
title_sort use of bleach baths for atopic dermatitis: an indian perspective
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644761/
https://www.ncbi.nlm.nih.gov/pubmed/36386066
http://dx.doi.org/10.4103/ijd.IJD_536_20
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