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ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart

BACKGROUND: Cardiovascular diseases have become the number one disease affecting human health in today's society. In the diagnosis of cardiac diseases, magnetic resonance image (MRI) technology is the most widely used one. However, in clinical diagnosis, the analysis of MRI relies on manual wor...

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Autores principales: Li, Yuanzhe, Liu, Zhiqiang, Lai, Qingquan, Li, Shuting, Guo, Yifan, Wang, Yi, Dai, Zhangsheng, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645148/
https://www.ncbi.nlm.nih.gov/pubmed/36386384
http://dx.doi.org/10.3389/fcvm.2022.1012450
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author Li, Yuanzhe
Liu, Zhiqiang
Lai, Qingquan
Li, Shuting
Guo, Yifan
Wang, Yi
Dai, Zhangsheng
Huang, Jing
author_facet Li, Yuanzhe
Liu, Zhiqiang
Lai, Qingquan
Li, Shuting
Guo, Yifan
Wang, Yi
Dai, Zhangsheng
Huang, Jing
author_sort Li, Yuanzhe
collection PubMed
description BACKGROUND: Cardiovascular diseases have become the number one disease affecting human health in today's society. In the diagnosis of cardiac diseases, magnetic resonance image (MRI) technology is the most widely used one. However, in clinical diagnosis, the analysis of MRI relies on manual work, which is laborious and time-consuming, and also easily influenced by the subjective experience of doctors. METHODS: In this article, we propose an artificial intelligence-aided diagnosis system for cardiac MRI with image segmentation as the main component to assist in the diagnosis of cardiovascular diseases. We first performed adequate pre-processing of MRI. The pre-processing steps include the detection of regions of interest of cardiac MRI data, as well as data normalization and data enhancement, and then we input the images after data pre-processing into the deep learning network module of ESA-Unet for the identification of the aorta in order to obtain preliminary segmentation results, and finally, the boundaries of the segmentation results are further optimized using conditional random fields. For ROI detection, we first use standard deviation filters for filtering to find regions in the heart cycle image sequence where pixel intensity varies strongly with time and then use Canny edge detection and Hough transform techniques to find the region of interest containing the heart. The ESA-Unet proposed in this article, moreover, is jointly designed with a self-attentive mechanism and multi-scale jump connection based on convolutional networks. RESULTS: The experimental dataset used in this article is from the Department of CT/MRI at the Second Affiliated Hospital of Fujian Medical University. Experiments compare other convolution-based methods, such as UNet, FCN, FPN, and PSPNet, and the results show that our model achieves the best results on Acc, Pr, ReCall, DSC, and IoU metrics. After comparative analysis, the experimental results show that the ESA-UNet network segmentation model designed in this article has higher accuracy, intuitiveness, and more application value than traditional image segmentation algorithms. CONCLUSION: With the continuous application of nuclear magnetic resonance technology in clinical diagnosis, the method in this article is expected to become a tool that can effectively improve the efficiency of doctors' diagnoses.
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spelling pubmed-96451482022-11-15 ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart Li, Yuanzhe Liu, Zhiqiang Lai, Qingquan Li, Shuting Guo, Yifan Wang, Yi Dai, Zhangsheng Huang, Jing Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Cardiovascular diseases have become the number one disease affecting human health in today's society. In the diagnosis of cardiac diseases, magnetic resonance image (MRI) technology is the most widely used one. However, in clinical diagnosis, the analysis of MRI relies on manual work, which is laborious and time-consuming, and also easily influenced by the subjective experience of doctors. METHODS: In this article, we propose an artificial intelligence-aided diagnosis system for cardiac MRI with image segmentation as the main component to assist in the diagnosis of cardiovascular diseases. We first performed adequate pre-processing of MRI. The pre-processing steps include the detection of regions of interest of cardiac MRI data, as well as data normalization and data enhancement, and then we input the images after data pre-processing into the deep learning network module of ESA-Unet for the identification of the aorta in order to obtain preliminary segmentation results, and finally, the boundaries of the segmentation results are further optimized using conditional random fields. For ROI detection, we first use standard deviation filters for filtering to find regions in the heart cycle image sequence where pixel intensity varies strongly with time and then use Canny edge detection and Hough transform techniques to find the region of interest containing the heart. The ESA-Unet proposed in this article, moreover, is jointly designed with a self-attentive mechanism and multi-scale jump connection based on convolutional networks. RESULTS: The experimental dataset used in this article is from the Department of CT/MRI at the Second Affiliated Hospital of Fujian Medical University. Experiments compare other convolution-based methods, such as UNet, FCN, FPN, and PSPNet, and the results show that our model achieves the best results on Acc, Pr, ReCall, DSC, and IoU metrics. After comparative analysis, the experimental results show that the ESA-UNet network segmentation model designed in this article has higher accuracy, intuitiveness, and more application value than traditional image segmentation algorithms. CONCLUSION: With the continuous application of nuclear magnetic resonance technology in clinical diagnosis, the method in this article is expected to become a tool that can effectively improve the efficiency of doctors' diagnoses. Frontiers Media S.A. 2022-10-26 /pmc/articles/PMC9645148/ /pubmed/36386384 http://dx.doi.org/10.3389/fcvm.2022.1012450 Text en Copyright © 2022 Li, Liu, Lai, Li, Guo, Wang, Dai and Huang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Li, Yuanzhe
Liu, Zhiqiang
Lai, Qingquan
Li, Shuting
Guo, Yifan
Wang, Yi
Dai, Zhangsheng
Huang, Jing
ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart
title ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart
title_full ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart
title_fullStr ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart
title_full_unstemmed ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart
title_short ESA-UNet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart
title_sort esa-unet for assisted diagnosis of cardiac magnetic resonance image based on the semantic segmentation of the heart
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645148/
https://www.ncbi.nlm.nih.gov/pubmed/36386384
http://dx.doi.org/10.3389/fcvm.2022.1012450
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