Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

Mitochondria are multifaceted organelles which are important for bioenergetics, biosynthesis, and signaling in metazoans. Mitochondrial functions are frequently altered in cancer to promote both the energy and the necessary metabolic intermediates for biosynthesis required for tumor growth. Cancer s...

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Detalles Bibliográficos
Autores principales: Greer, Yoshimi Endo, Hernandez, Lidia, Fennell, Emily M.J., Kundu, Manjari, Voeller, Donna, Chari, Raj, Gilbert, Samuel F., Gilbert, Thomas S.K., Ratnayake, Shashikala, Tang, Binwu, Hafner, Markus, Chen, Qingrong, Meerzaman, Daoud, Iwanowicz, Edwin, Annunziata, Christina M., Graves, Lee M., Lipkowitz, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645232/
https://www.ncbi.nlm.nih.gov/pubmed/36388465
http://dx.doi.org/10.1158/2767-9764.CRC-22-0142

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