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Single-Cell Transcriptomic Profiling of Human Retinal Organoids Revealed a Role of IGF1-PHLDA1 Axis in Photoreceptor Precursor Specification

PURPOSE: Cone and rod photoreceptors in the retina convert light to electrical signals which are transmitted to the visual cortex of the brain. Abnormal photoreceptor development and degeneration results in blindness. So far, the mechanism that controls photoreceptor specification and its subsequent...

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Detalles Bibliográficos
Autores principales:	Xiao, Yuhua, Mao, Xiying, Hu, Xing, Yuan, Songtao, Chen, Xu, Dai, Wangxuan, Zhang, Shuyao, Li, Yonghua, Chen, Mingkang, Mao, Peiyao, Liu, Yizhi, Liu, Qinghuai, Hu, Youjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645368/ https://www.ncbi.nlm.nih.gov/pubmed/36331259 http://dx.doi.org/10.1167/iovs.63.12.9

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