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Tyrosine bioconjugation with hypervalent iodine

Hypervalent iodine reagents have recently emerged as powerful tools for late-stage peptide and protein functionalization. Herein we report a tyrosine bioconjugation methodology for the introduction of hypervalent iodine onto biomolecules under physiological conditions. Tyrosine residues were engaged...

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Detalles Bibliográficos
Autores principales: Declas, Nina, Maynard, John R. J., Menin, Laure, Gasilova, Natalia, Götze, Sebastian, Sprague, Jakob L., Stallforth, Pierre, Matile, Stefan, Waser, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645396/
https://www.ncbi.nlm.nih.gov/pubmed/36519034
http://dx.doi.org/10.1039/d2sc04558c