Resistance and phylogeny guided discovery reveals structural novelty of tetracycline antibiotics

Tetracyclines are a class of antibiotics that exhibited potent activity against a wide range of Gram-positive and Gram-negative bacteria, yet only five members were isolated from actinobacteria, with two of them approved as clinical drugs. In this work, we developed a genome mining strategy using a...

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Detalles Bibliográficos
Autores principales: Li, Ling Yu, Hu, Yi Ling, Sun, Jia Lin, Yu, Long Bo, Shi, Jing, Wang, Zi Ru, Guo, Zhi Kai, Zhang, Bo, Guo, Wen Jie, Tan, Ren Xiang, Ge, Hui Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645399/
https://www.ncbi.nlm.nih.gov/pubmed/36519048
http://dx.doi.org/10.1039/d2sc03965f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645399/
https://www.ncbi.nlm.nih.gov/pubmed/36519048
http://dx.doi.org/10.1039/d2sc03965f

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