Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups

Multivalent antigen display is a fast-growing area of interest towards broadly protective vaccines. Current nanoparticle-based vaccine candidates demonstrate the ability to confer antibody-mediated immunity against divergent strains of notably mutable viruses. In coronaviruses, this work is predomin...

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Detalles Bibliográficos
Autores principales: Hutchinson, Geoffrey, Abiona, Olubukola, Ziwawo, Cynthia, Werner, Anne, Ellis, Daniel, Tsybovsky, Yaroslav, Leist, Sarah, Palandjian, Charis, West, Ande, Fritch, Ethan, Wang, Niangshuang, Wrapp, Daniel, Boyoglu-Barnum, Seyhan, Ueda, George, Baker, David, Kanekiyo, Masaru, McLellan, Jason, Baric, Ralph, King, Neil, Graham, Barney, Corbett, Kizzmekia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645427/
https://www.ncbi.nlm.nih.gov/pubmed/36380759
http://dx.doi.org/10.21203/rs.3.rs-2199814/v1

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