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Ydj1 interaction at nucleotide-binding-domain of yeast Ssa1 impacts Hsp90 collaboration and client maturation

Hsp90 constitutes one of the major chaperone machinery in the cell. The Hsp70 assists Hsp90 in its client maturation though the underlying basis of the Hsp70 role remains to be explored. In the present study, using S. cerevisiae strain expressing Ssa1 as sole Ssa Hsp70, we identified novel mutations...

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Detalles Bibliográficos
Autores principales: Gaur, Deepika, Kumar, Navinder, Ghosh, Abhirupa, Singh, Prashant, Kumar, Pradeep, Guleria, Jyoti, Kaur, Satinderdeep, Malik, Nikhil, Saha, Sudipto, Nystrom, Thomas, Sharma, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645627/
https://www.ncbi.nlm.nih.gov/pubmed/36350833
http://dx.doi.org/10.1371/journal.pgen.1010442