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Cryo-EM structure of the human sodium-chloride cotransporter NCC

The sodium-chloride cotransporter NCC mediates the coupled import of sodium and chloride across the plasma membrane, playing vital roles in kidney extracellular fluid volume and blood pressure control. Here, we present the full-length structure of human NCC, with 2.9 Å for the transmembrane domain a...

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Detalles Bibliográficos
Autores principales:	Nan, Jing, Yuan, Yafei, Yang, Xuemei, Shan, Ziyang, Liu, Huihui, Wei, Feiwen, Zhang, Wei, Zhang, Yanqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645730/ https://www.ncbi.nlm.nih.gov/pubmed/36351028 http://dx.doi.org/10.1126/sciadv.add7176

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