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Orthopaedic Management of Gout
Gout is characterized by the deposition of monosodium urate crystals in patients with chronically elevated blood levels of uric acid. It is the most common form of inflammatory arthritis in the United States and is often comorbid with hypertension, obesity, and chronic kidney disease. Initial presen...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645791/ https://www.ncbi.nlm.nih.gov/pubmed/36346841 http://dx.doi.org/10.5435/JAAOSGlobal-D-22-00216 |
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author | Cohen-Rosenblum, Anna R. Somogyi, Jason R. Hynes, Kelly K. Guevara, Myriam E. |
author_facet | Cohen-Rosenblum, Anna R. Somogyi, Jason R. Hynes, Kelly K. Guevara, Myriam E. |
author_sort | Cohen-Rosenblum, Anna R. |
collection | PubMed |
description | Gout is characterized by the deposition of monosodium urate crystals in patients with chronically elevated blood levels of uric acid. It is the most common form of inflammatory arthritis in the United States and is often comorbid with hypertension, obesity, and chronic kidney disease. Initial presentation is usually an acutely warm, swollen joint, most commonly the first metatarsophalangeal joint, but a variety of locations may be affected. The main treatment for gout is medical management of acute inflammation and chronic uric acid levels, but surgical treatment may be indicated in cases of damage to the surrounding soft tissue, concomitant septic arthritis, symptomatic cartilage loss, or neurologic deficits. Based on the literature to date, gout does not seem to independently affect outcomes after total hip, knee, and ankle arthroplasty, but associated comorbidities affecting outcomes in these patients should be considered. |
format | Online Article Text |
id | pubmed-9645791 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer |
record_format | MEDLINE/PubMed |
spelling | pubmed-96457912022-11-14 Orthopaedic Management of Gout Cohen-Rosenblum, Anna R. Somogyi, Jason R. Hynes, Kelly K. Guevara, Myriam E. J Am Acad Orthop Surg Glob Res Rev Review Article Gout is characterized by the deposition of monosodium urate crystals in patients with chronically elevated blood levels of uric acid. It is the most common form of inflammatory arthritis in the United States and is often comorbid with hypertension, obesity, and chronic kidney disease. Initial presentation is usually an acutely warm, swollen joint, most commonly the first metatarsophalangeal joint, but a variety of locations may be affected. The main treatment for gout is medical management of acute inflammation and chronic uric acid levels, but surgical treatment may be indicated in cases of damage to the surrounding soft tissue, concomitant septic arthritis, symptomatic cartilage loss, or neurologic deficits. Based on the literature to date, gout does not seem to independently affect outcomes after total hip, knee, and ankle arthroplasty, but associated comorbidities affecting outcomes in these patients should be considered. Wolters Kluwer 2022-11-08 /pmc/articles/PMC9645791/ /pubmed/36346841 http://dx.doi.org/10.5435/JAAOSGlobal-D-22-00216 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Cohen-Rosenblum, Anna R. Somogyi, Jason R. Hynes, Kelly K. Guevara, Myriam E. Orthopaedic Management of Gout |
title | Orthopaedic Management of Gout |
title_full | Orthopaedic Management of Gout |
title_fullStr | Orthopaedic Management of Gout |
title_full_unstemmed | Orthopaedic Management of Gout |
title_short | Orthopaedic Management of Gout |
title_sort | orthopaedic management of gout |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645791/ https://www.ncbi.nlm.nih.gov/pubmed/36346841 http://dx.doi.org/10.5435/JAAOSGlobal-D-22-00216 |
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