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Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism

Cat scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae typically resulting in self-limited regional lymphadenopathy. Encephalitis is a complication with a supposedly benign prognosis, but we encountered an exceptional case. A 19-year-old Japanese woman presented with status...

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Autores principales: Nakamura, Masakazu, Ura, Shigehisa, Yabe, Ichiro, Otsuki, Mika, Soma, Hiroyuki, Ogata, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646356/
https://www.ncbi.nlm.nih.gov/pubmed/35314550
http://dx.doi.org/10.2169/internalmedicine.9047-21
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author Nakamura, Masakazu
Ura, Shigehisa
Yabe, Ichiro
Otsuki, Mika
Soma, Hiroyuki
Ogata, Akihiko
author_facet Nakamura, Masakazu
Ura, Shigehisa
Yabe, Ichiro
Otsuki, Mika
Soma, Hiroyuki
Ogata, Akihiko
author_sort Nakamura, Masakazu
collection PubMed
description Cat scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae typically resulting in self-limited regional lymphadenopathy. Encephalitis is a complication with a supposedly benign prognosis, but we encountered an exceptional case. A 19-year-old Japanese woman presented with status epilepticus. She was diagnosed with CSD-associated encephalitis based on her history of contact with a kitten and a high titre of serum IgG to B. henselae. Multimodal treatment ameliorated her encephalitis, but neurological sequelae including spastic paraparesis, persisted. After several months, she developed age-disproportionate parkinsonism inconsistent with a neurodegenerative disease. In conclusion, CSD-associated encephalitis can result in severe neurological sequelae and post-encephalitic parkinsonism.
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spelling pubmed-96463562022-11-18 Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism Nakamura, Masakazu Ura, Shigehisa Yabe, Ichiro Otsuki, Mika Soma, Hiroyuki Ogata, Akihiko Intern Med Case Report Cat scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae typically resulting in self-limited regional lymphadenopathy. Encephalitis is a complication with a supposedly benign prognosis, but we encountered an exceptional case. A 19-year-old Japanese woman presented with status epilepticus. She was diagnosed with CSD-associated encephalitis based on her history of contact with a kitten and a high titre of serum IgG to B. henselae. Multimodal treatment ameliorated her encephalitis, but neurological sequelae including spastic paraparesis, persisted. After several months, she developed age-disproportionate parkinsonism inconsistent with a neurodegenerative disease. In conclusion, CSD-associated encephalitis can result in severe neurological sequelae and post-encephalitic parkinsonism. The Japanese Society of Internal Medicine 2022-03-19 2022-10-15 /pmc/articles/PMC9646356/ /pubmed/35314550 http://dx.doi.org/10.2169/internalmedicine.9047-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nakamura, Masakazu
Ura, Shigehisa
Yabe, Ichiro
Otsuki, Mika
Soma, Hiroyuki
Ogata, Akihiko
Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism
title Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism
title_full Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism
title_fullStr Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism
title_full_unstemmed Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism
title_short Cat Scratch Disease-associated Encephalitis Followed by Parkinsonism
title_sort cat scratch disease-associated encephalitis followed by parkinsonism
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646356/
https://www.ncbi.nlm.nih.gov/pubmed/35314550
http://dx.doi.org/10.2169/internalmedicine.9047-21
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