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THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS

INTRODUCTION: Asthma is the most common chronic disease in children, with about 1 in 20 asthmatic children annually hospitalized for an exacerbation. Since respiratory viruses are common exacerbation triggers, there were concerns that SARS-CoV2 would lead to increased asthma admissions. We hypothesi...

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Autores principales: Raja, S., Nguyen, V., Heinle, R., Hossain, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646428/
http://dx.doi.org/10.1016/j.anai.2022.08.638
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author Raja, S.
Nguyen, V.
Heinle, R.
Hossain, J.
author_facet Raja, S.
Nguyen, V.
Heinle, R.
Hossain, J.
author_sort Raja, S.
collection PubMed
description INTRODUCTION: Asthma is the most common chronic disease in children, with about 1 in 20 asthmatic children annually hospitalized for an exacerbation. Since respiratory viruses are common exacerbation triggers, there were concerns that SARS-CoV2 would lead to increased asthma admissions. We hypothesized that the CDC-implemented pandemic isolation measures would instead lead to a decrease in asthma admissions by limiting the spread of other respiratory viruses. METHODS: A retrospective chart review at a pediatric tertiary care center was conducted. Monthly asthma-related hospitalizations of patients 2-18 years of age were counted. Patients with tracheostomy or ventilator dependence were excluded. Admissions from the start of the pandemic in March 2020 until present were compared to baseline data from the 2 years preceding the pandemic. A Chi-square test was used to compare the uniformity of annual admissions and month-by-month admissions over 5 years. RESULTS: There were 4703 asthma admissions over the 5-year period. There was a statistically significant (p<0.001) decrease in the number of monthly asthma admissions during March 2020-June 2020, when the strictest isolation measures were in place. This decrease, compared to baseline data, persisted for approximately 12 months until again returning to baseline data in Spring 2021, as isolation measures eased. A lower magnitude and shorter duration decrease from baseline admissions was also seen during the Omicron spike. CONCLUSION: Asthma admissions sharply declined during the strictest isolation measures and then returned to baseline levels as the measures eased. This data suggests that isolation measures may reduce respiratory virus transmission and contribute toward reduced pediatric asthma admissions.
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spelling pubmed-96464282022-11-14 THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS Raja, S. Nguyen, V. Heinle, R. Hossain, J. Ann Allergy Asthma Immunol P116 INTRODUCTION: Asthma is the most common chronic disease in children, with about 1 in 20 asthmatic children annually hospitalized for an exacerbation. Since respiratory viruses are common exacerbation triggers, there were concerns that SARS-CoV2 would lead to increased asthma admissions. We hypothesized that the CDC-implemented pandemic isolation measures would instead lead to a decrease in asthma admissions by limiting the spread of other respiratory viruses. METHODS: A retrospective chart review at a pediatric tertiary care center was conducted. Monthly asthma-related hospitalizations of patients 2-18 years of age were counted. Patients with tracheostomy or ventilator dependence were excluded. Admissions from the start of the pandemic in March 2020 until present were compared to baseline data from the 2 years preceding the pandemic. A Chi-square test was used to compare the uniformity of annual admissions and month-by-month admissions over 5 years. RESULTS: There were 4703 asthma admissions over the 5-year period. There was a statistically significant (p<0.001) decrease in the number of monthly asthma admissions during March 2020-June 2020, when the strictest isolation measures were in place. This decrease, compared to baseline data, persisted for approximately 12 months until again returning to baseline data in Spring 2021, as isolation measures eased. A lower magnitude and shorter duration decrease from baseline admissions was also seen during the Omicron spike. CONCLUSION: Asthma admissions sharply declined during the strictest isolation measures and then returned to baseline levels as the measures eased. This data suggests that isolation measures may reduce respiratory virus transmission and contribute toward reduced pediatric asthma admissions. Published by Elsevier Inc. 2022-11 2022-11-10 /pmc/articles/PMC9646428/ http://dx.doi.org/10.1016/j.anai.2022.08.638 Text en Copyright © 2022 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle P116
Raja, S.
Nguyen, V.
Heinle, R.
Hossain, J.
THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS
title THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS
title_full THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS
title_fullStr THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS
title_full_unstemmed THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS
title_short THE IMPACT OF COVID-19 PANDEMIC ISOLATION MEASURES ON PEDIATRIC ASTHMA ADMISSIONS
title_sort impact of covid-19 pandemic isolation measures on pediatric asthma admissions
topic P116
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646428/
http://dx.doi.org/10.1016/j.anai.2022.08.638
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