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Variant to function mapping at single-cell resolution through network propagation
Genome-wide association studies in combination with single-cell genomic atlases can provide insights into the mechanisms of disease-causal genetic variation. However, identification of disease-relevant or trait-relevant cell types, states and trajectories is often hampered by sparsity and noise, par...
Autores principales: | Yu, Fulong, Cato, Liam D., Weng, Chen, Liggett, L. Alexander, Jeon, Soyoung, Xu, Keren, Chiang, Charleston W. K., Wiemels, Joseph L., Weissman, Jonathan S., de Smith, Adam J., Sankaran, Vijay G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646486/ https://www.ncbi.nlm.nih.gov/pubmed/35668323 http://dx.doi.org/10.1038/s41587-022-01341-y |
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