Variant to function mapping at single-cell resolution through network propagation

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Genome-wide association studies in combination with single-cell genomic atlases can provide insights into the mechanisms of disease-causal genetic variation. However, identification of disease-relevant or trait-relevant cell types, states and trajectories is often hampered by sparsity and noise, par...

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Detalles Bibliográficos
Autores principales: Yu, Fulong, Cato, Liam D., Weng, Chen, Liggett, L. Alexander, Jeon, Soyoung, Xu, Keren, Chiang, Charleston W. K., Wiemels, Joseph L., Weissman, Jonathan S., de Smith, Adam J., Sankaran, Vijay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646486/
https://www.ncbi.nlm.nih.gov/pubmed/35668323
http://dx.doi.org/10.1038/s41587-022-01341-y
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