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Directed evolution and selection of biostable l-DNA aptamers with a mirror-image DNA polymerase

Mirror-image aptamers made from chirally inverted nucleic acids are nuclease-resistant and exceptionally biostable, opening up opportunities for unique applications. However, the directed evolution and selection of mirror-image aptamers directly from large randomized l-DNA libraries has, to our kno...

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Detalles Bibliográficos
Autores principales:	Chen, Ji, Chen, Mengyin, Zhu, Ting F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646512/ https://www.ncbi.nlm.nih.gov/pubmed/35668324 http://dx.doi.org/10.1038/s41587-022-01337-8

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