Bending forces and nucleotide state jointly regulate F-actin structure

ATP-hydrolysis-coupled actin polymerization is a fundamental mechanism of cellular force generation(1–3). In turn, force(4,5) and actin filament (F-actin) nucleotide state(6) regulate actin dynamics by tuning F-actin’s engagement of actin-binding proteins through mechanisms that are unclear. Here we...

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Detalles Bibliográficos
Autores principales: Reynolds, Matthew J., Hachicho, Carla, Carl, Ayala G., Gong, Rui, Alushin, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646526/
https://www.ncbi.nlm.nih.gov/pubmed/36289330
http://dx.doi.org/10.1038/s41586-022-05366-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646526/
https://www.ncbi.nlm.nih.gov/pubmed/36289330
http://dx.doi.org/10.1038/s41586-022-05366-w

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