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Bending forces and nucleotide state jointly regulate F-actin structure
ATP-hydrolysis-coupled actin polymerization is a fundamental mechanism of cellular force generation(1–3). In turn, force(4,5) and actin filament (F-actin) nucleotide state(6) regulate actin dynamics by tuning F-actin’s engagement of actin-binding proteins through mechanisms that are unclear. Here we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646526/ https://www.ncbi.nlm.nih.gov/pubmed/36289330 http://dx.doi.org/10.1038/s41586-022-05366-w |