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Phenotyping of Fecal Microbiota of Winnie, a Rodent Model of Spontaneous Chronic Colitis, Reveals Specific Metabolic, Genotoxic, and Pro-inflammatory Properties

Winnie, a mouse carrying a missense mutation in the MUC2 mucin gene, is a valuable model for inflammatory bowel disease (IBD) with signs and symptoms that have multiple similarities with those observed in patients with ulcerative colitis. MUC2 mucin is present in Winnie, but is not firmly compacted...

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Detalles Bibliográficos
Autores principales: Talà, Adelfia, Guerra, Flora, Resta, Silvia Caterina, Calcagnile, Matteo, Barca, Amilcare, Tredici, Salvatore Maurizio, De Donno, Maria Dolores, Vacca, Mirco, Liso, Marina, Chieppa, Marcello, De Angelis, Maria, Verri, Tiziano, Bozzetti, Maria Giuseppina, Bucci, Cecilia, Alifano, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646540/
https://www.ncbi.nlm.nih.gov/pubmed/35732858
http://dx.doi.org/10.1007/s10753-022-01706-0

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