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Serum pro-oxidant/antioxidant balance in term versus preterm neonates
The oxidant/antioxidant status balance is a process that begins before birth and premature infants are particularly susceptible to oxidative stress. According to the mechanisms of oxidative stress and lack of study in this field, in this prospective study, we aimed to compare the levels of serum pro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646564/ https://www.ncbi.nlm.nih.gov/pubmed/36343075 http://dx.doi.org/10.1097/MD.0000000000031381 |
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author | Boskabadi, Hassan Ghayour-Mobarhan, Majid Saeidinia, Amin |
author_facet | Boskabadi, Hassan Ghayour-Mobarhan, Majid Saeidinia, Amin |
author_sort | Boskabadi, Hassan |
collection | PubMed |
description | The oxidant/antioxidant status balance is a process that begins before birth and premature infants are particularly susceptible to oxidative stress. According to the mechanisms of oxidative stress and lack of study in this field, in this prospective study, we aimed to compare the levels of serum pro-oxidant/antioxidant balance (PAB) in preterm versus term babies. This was a prospective cross-sectional study that was performed in Ghaem hospital, a university tertiary hospital, in Mashhad, Iran. The study population included all term and preterm neonates who were admitted to the hospital within birth time. In our study, 324 neonates were included. One hundred ninety-eight neonates were preterm (61.1%) and others were term (38.9%). There was a significant difference between PAB levels in term and preterm neonates. Serum PAB level was significantly lower in preterm neonates rather than in term neonates (21.86 ± 21.01 vs 50.33 ± 31.69; P = .001). There was also a significant negative correlation between PAB levels and gestational age. According to previous investigations, we showed for the first time in our study that PAB is lower in preterm newborns rather than in term ones. |
format | Online Article Text |
id | pubmed-9646564 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-96465642022-11-14 Serum pro-oxidant/antioxidant balance in term versus preterm neonates Boskabadi, Hassan Ghayour-Mobarhan, Majid Saeidinia, Amin Medicine (Baltimore) 6200 The oxidant/antioxidant status balance is a process that begins before birth and premature infants are particularly susceptible to oxidative stress. According to the mechanisms of oxidative stress and lack of study in this field, in this prospective study, we aimed to compare the levels of serum pro-oxidant/antioxidant balance (PAB) in preterm versus term babies. This was a prospective cross-sectional study that was performed in Ghaem hospital, a university tertiary hospital, in Mashhad, Iran. The study population included all term and preterm neonates who were admitted to the hospital within birth time. In our study, 324 neonates were included. One hundred ninety-eight neonates were preterm (61.1%) and others were term (38.9%). There was a significant difference between PAB levels in term and preterm neonates. Serum PAB level was significantly lower in preterm neonates rather than in term neonates (21.86 ± 21.01 vs 50.33 ± 31.69; P = .001). There was also a significant negative correlation between PAB levels and gestational age. According to previous investigations, we showed for the first time in our study that PAB is lower in preterm newborns rather than in term ones. Lippincott Williams & Wilkins 2022-11-04 /pmc/articles/PMC9646564/ /pubmed/36343075 http://dx.doi.org/10.1097/MD.0000000000031381 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 6200 Boskabadi, Hassan Ghayour-Mobarhan, Majid Saeidinia, Amin Serum pro-oxidant/antioxidant balance in term versus preterm neonates |
title | Serum pro-oxidant/antioxidant balance in term versus preterm neonates |
title_full | Serum pro-oxidant/antioxidant balance in term versus preterm neonates |
title_fullStr | Serum pro-oxidant/antioxidant balance in term versus preterm neonates |
title_full_unstemmed | Serum pro-oxidant/antioxidant balance in term versus preterm neonates |
title_short | Serum pro-oxidant/antioxidant balance in term versus preterm neonates |
title_sort | serum pro-oxidant/antioxidant balance in term versus preterm neonates |
topic | 6200 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646564/ https://www.ncbi.nlm.nih.gov/pubmed/36343075 http://dx.doi.org/10.1097/MD.0000000000031381 |
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