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Inhibition of BRD4 enhanced the tumor suppression effect of dasatinib in gastric cancer
BRD4, a member of the bromodomain and extraterminal (BET) family, is elevated in multiple cancer tissues, including gastric cancer (GC). Targeted therapy with BRD4 may help improve the overall survival of patients with GC. Meanwhile, the approved multi-target kinase inhibitor, dasatinib, was recentl...
Autores principales: | Shen, Hao, Hu, Xuefei, Yang, Xinrui, Chen, Jiahui, Fu, Yating, He, Hongwei, Shi, Yongkang, Zeng, Rong, Chang, Wenjun, Zheng, Shangyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646567/ https://www.ncbi.nlm.nih.gov/pubmed/36352160 http://dx.doi.org/10.1007/s12032-022-01831-8 |
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