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Effect of cataract surgery on the progression of age-related macular degeneration

Cataracts and age-related macular degeneration (AMD) are common causes of decreased vision and blindness in individuals over age 50. Although surgery is the most effective treatment for cataracts, it may accelerate the progression of AMD, so this study further evaluated the influence of cataract sur...

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Autores principales: Chen, Zhaoyan, Zeng, Ya, Tian, Fangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646653/
https://www.ncbi.nlm.nih.gov/pubmed/36343088
http://dx.doi.org/10.1097/MD.0000000000031566
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author Chen, Zhaoyan
Zeng, Ya
Tian, Fangyuan
author_facet Chen, Zhaoyan
Zeng, Ya
Tian, Fangyuan
author_sort Chen, Zhaoyan
collection PubMed
description Cataracts and age-related macular degeneration (AMD) are common causes of decreased vision and blindness in individuals over age 50. Although surgery is the most effective treatment for cataracts, it may accelerate the progression of AMD, so this study further evaluated the influence of cataract surgery for AMD through a systematic review and meta-analysis. METHODS: The Cochrane Systematic Evaluation method was adopted, and computer searches were conducted for the China Knowledge Network, Wanfang, Vipul, SinoMed, PubMed, SpringerLink, Clinicalkey, Medline, Cochrane Library, Web of Science, OVID, and Embase databases of cohort studies on the impact of cataract surgery on AMD, with search timeframes up to May 2022. Meta-analysis was performed using Stata/12.0. RESULTS: A total of 8 cohort studies were included in the study. The results showed that the relative risk (RR) of AMD progression after cataract surgery was not significantly different, RR 1.194 [95% credibility interval (CI) 0.897‐1.591]; the risk remained increased more than 5 years after surgery, RR 1.372 (95% CI 1.062‐1.772). CONCLUSION: There is still a significant positive correlation between cataract surgery and increase the risk of worsening of AMD progression, and faster progression of early-to-late AMD found in cataract surgery with longer follow-up of patients.
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spelling pubmed-96466532022-11-14 Effect of cataract surgery on the progression of age-related macular degeneration Chen, Zhaoyan Zeng, Ya Tian, Fangyuan Medicine (Baltimore) 6000 Cataracts and age-related macular degeneration (AMD) are common causes of decreased vision and blindness in individuals over age 50. Although surgery is the most effective treatment for cataracts, it may accelerate the progression of AMD, so this study further evaluated the influence of cataract surgery for AMD through a systematic review and meta-analysis. METHODS: The Cochrane Systematic Evaluation method was adopted, and computer searches were conducted for the China Knowledge Network, Wanfang, Vipul, SinoMed, PubMed, SpringerLink, Clinicalkey, Medline, Cochrane Library, Web of Science, OVID, and Embase databases of cohort studies on the impact of cataract surgery on AMD, with search timeframes up to May 2022. Meta-analysis was performed using Stata/12.0. RESULTS: A total of 8 cohort studies were included in the study. The results showed that the relative risk (RR) of AMD progression after cataract surgery was not significantly different, RR 1.194 [95% credibility interval (CI) 0.897‐1.591]; the risk remained increased more than 5 years after surgery, RR 1.372 (95% CI 1.062‐1.772). CONCLUSION: There is still a significant positive correlation between cataract surgery and increase the risk of worsening of AMD progression, and faster progression of early-to-late AMD found in cataract surgery with longer follow-up of patients. Lippincott Williams & Wilkins 2022-11-04 /pmc/articles/PMC9646653/ /pubmed/36343088 http://dx.doi.org/10.1097/MD.0000000000031566 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 6000
Chen, Zhaoyan
Zeng, Ya
Tian, Fangyuan
Effect of cataract surgery on the progression of age-related macular degeneration
title Effect of cataract surgery on the progression of age-related macular degeneration
title_full Effect of cataract surgery on the progression of age-related macular degeneration
title_fullStr Effect of cataract surgery on the progression of age-related macular degeneration
title_full_unstemmed Effect of cataract surgery on the progression of age-related macular degeneration
title_short Effect of cataract surgery on the progression of age-related macular degeneration
title_sort effect of cataract surgery on the progression of age-related macular degeneration
topic 6000
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646653/
https://www.ncbi.nlm.nih.gov/pubmed/36343088
http://dx.doi.org/10.1097/MD.0000000000031566
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