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A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections

The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the environment. This paper proposes a biomimetic ocular prosthesis system that mimics the human light modulation response capable of pupil and corneal reflections. First,...

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Detalles Bibliográficos
Autores principales: Kim, Seongchan, Choi, Yoon Young, Kim, Taewan, Kim, Yong Min, Ho, Dong Hae, Choi, Young Jin, Roe, Dong Gue, Lee, Ju-Hee, Park, Joongpill, Choi, Ji-Woong, Kim, Jeong Won, Park, Jin-Hong, Jo, Sae Byeok, Moon, Hong Chul, Jeong, Sohee, Cho, Jeong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646703/
https://www.ncbi.nlm.nih.gov/pubmed/36351937
http://dx.doi.org/10.1038/s41467-022-34448-6
Descripción
Sumario:The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the environment. This paper proposes a biomimetic ocular prosthesis system that mimics the human light modulation response capable of pupil and corneal reflections. First, photoinduced synaptic properties of the quantum dot embedded photonic synapse and its biosimilar signal transmission is confirmed. Subsequently, the pupillary light reflex is emulated by incorporating the quantum dot embedded photonic synapse, electrochromic device, and CMOS components. Moreover, a solenoid-based eyelid is connected to the pupillary light reflex system to emulate the corneal reflex. The proposed ocular prosthesis system represents a platform for biomimetic prosthesis that can accommodate an appropriate amount of stimulus by self-regulating the intensity of external stimuli.