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A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections

The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the environment. This paper proposes a biomimetic ocular prosthesis system that mimics the human light modulation response capable of pupil and corneal reflections. First,...

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Autores principales: Kim, Seongchan, Choi, Yoon Young, Kim, Taewan, Kim, Yong Min, Ho, Dong Hae, Choi, Young Jin, Roe, Dong Gue, Lee, Ju-Hee, Park, Joongpill, Choi, Ji-Woong, Kim, Jeong Won, Park, Jin-Hong, Jo, Sae Byeok, Moon, Hong Chul, Jeong, Sohee, Cho, Jeong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646703/
https://www.ncbi.nlm.nih.gov/pubmed/36351937
http://dx.doi.org/10.1038/s41467-022-34448-6
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author Kim, Seongchan
Choi, Yoon Young
Kim, Taewan
Kim, Yong Min
Ho, Dong Hae
Choi, Young Jin
Roe, Dong Gue
Lee, Ju-Hee
Park, Joongpill
Choi, Ji-Woong
Kim, Jeong Won
Park, Jin-Hong
Jo, Sae Byeok
Moon, Hong Chul
Jeong, Sohee
Cho, Jeong Ho
author_facet Kim, Seongchan
Choi, Yoon Young
Kim, Taewan
Kim, Yong Min
Ho, Dong Hae
Choi, Young Jin
Roe, Dong Gue
Lee, Ju-Hee
Park, Joongpill
Choi, Ji-Woong
Kim, Jeong Won
Park, Jin-Hong
Jo, Sae Byeok
Moon, Hong Chul
Jeong, Sohee
Cho, Jeong Ho
author_sort Kim, Seongchan
collection PubMed
description The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the environment. This paper proposes a biomimetic ocular prosthesis system that mimics the human light modulation response capable of pupil and corneal reflections. First, photoinduced synaptic properties of the quantum dot embedded photonic synapse and its biosimilar signal transmission is confirmed. Subsequently, the pupillary light reflex is emulated by incorporating the quantum dot embedded photonic synapse, electrochromic device, and CMOS components. Moreover, a solenoid-based eyelid is connected to the pupillary light reflex system to emulate the corneal reflex. The proposed ocular prosthesis system represents a platform for biomimetic prosthesis that can accommodate an appropriate amount of stimulus by self-regulating the intensity of external stimuli.
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spelling pubmed-96467032022-11-15 A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections Kim, Seongchan Choi, Yoon Young Kim, Taewan Kim, Yong Min Ho, Dong Hae Choi, Young Jin Roe, Dong Gue Lee, Ju-Hee Park, Joongpill Choi, Ji-Woong Kim, Jeong Won Park, Jin-Hong Jo, Sae Byeok Moon, Hong Chul Jeong, Sohee Cho, Jeong Ho Nat Commun Article The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the environment. This paper proposes a biomimetic ocular prosthesis system that mimics the human light modulation response capable of pupil and corneal reflections. First, photoinduced synaptic properties of the quantum dot embedded photonic synapse and its biosimilar signal transmission is confirmed. Subsequently, the pupillary light reflex is emulated by incorporating the quantum dot embedded photonic synapse, electrochromic device, and CMOS components. Moreover, a solenoid-based eyelid is connected to the pupillary light reflex system to emulate the corneal reflex. The proposed ocular prosthesis system represents a platform for biomimetic prosthesis that can accommodate an appropriate amount of stimulus by self-regulating the intensity of external stimuli. Nature Publishing Group UK 2022-11-09 /pmc/articles/PMC9646703/ /pubmed/36351937 http://dx.doi.org/10.1038/s41467-022-34448-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kim, Seongchan
Choi, Yoon Young
Kim, Taewan
Kim, Yong Min
Ho, Dong Hae
Choi, Young Jin
Roe, Dong Gue
Lee, Ju-Hee
Park, Joongpill
Choi, Ji-Woong
Kim, Jeong Won
Park, Jin-Hong
Jo, Sae Byeok
Moon, Hong Chul
Jeong, Sohee
Cho, Jeong Ho
A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
title A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
title_full A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
title_fullStr A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
title_full_unstemmed A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
title_short A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
title_sort biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646703/
https://www.ncbi.nlm.nih.gov/pubmed/36351937
http://dx.doi.org/10.1038/s41467-022-34448-6
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