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A randomized pharmacological fMRI trial investigating d-cycloserine and brain plasticity mechanisms in learned pain responses

Learning and negative outcome expectations can increase pain sensitivity, a phenomenon known as nocebo hyperalgesia. Here, we examined how a targeted pharmacological manipulation of learning would impact nocebo responses and their brain correlates. Participants received either a placebo (n = 27) or...

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Detalles Bibliográficos
Autores principales: Thomaidou, Mia A., Blythe, Joseph S., Veldhuijzen, Dieuwke S., Peerdeman, Kaya J., van Lennep, Johan (Hans) P. A., Giltay, Erik J., Cremers, Henk R., Evers, Andrea W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646732/
https://www.ncbi.nlm.nih.gov/pubmed/36351953
http://dx.doi.org/10.1038/s41598-022-23769-7